DDX42 and RECQL5

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DDX42	RECQL5
Description		DEAD-box helicase 42	RecQ like helicase 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Membrane Nuclear Speck	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol RNA Polymerase II, Holoenzyme
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding	RNA Polymerase II Complex Binding Nucleic Acid Binding DNA Helicase Activity ATP Binding Four-way Junction Helicase Activity 3'-5' DNA Helicase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Protein Localization Regulation Of Apoptotic Process	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination DNA Metabolic Process DNA Replication DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cellular Response To Drug Cell Division Chromosome Separation Cellular Response To Camptothecin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Body mass index ( 25673413) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 25673412)	Deep white matter hyperintensities ( 32517579) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		10 interacting genes: APP DHX15 FBXO25 MDM2 PRPF19 RECQL5 SF3A1 SF3B4 SNRPC U2SURP	20 interacting genes: ADCY10P1 ALDH7A1 BNIPL CREB1 CUX1 DDX42 EEF1G ITGB3BP MAPK8IP1 MRE11 MTSS1 MUS81 NBN PLK1 RAD50 RAD51 STAMBP TIMP1 TOP3A TOP3B
Entrez ID		11325	9400
HPRD ID		09909	04806
Ensembl ID		ENSG00000198231	ENSG00000108469
Uniprot IDs		Q86XP3	A0A024R8M9 A0A024R8S8 B3KQK2 O94762 Q8WYH5
PDB IDs			4BK0 5LB3 5LB5 5LB8 5LBA
Enriched GO Terms of Interacting Partners?
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