AHNAK2 and CYB5B

Data Source:
BioGRID (two hybrid)

		AHNAK2	CYB5B
Description		AHNAK nucleoprotein 2	cytochrome b5 type B
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Z Disc T-tubule Cytoplasmic Vesicle Membrane Sarcolemma Costamere	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding	Protein Binding Enzyme Activator Activity Electron Transfer Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity
	Biological Process	Plasma Membrane Repair Regulation Of RNA Splicing	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Electron Transport Chain Regulation Of Catalytic Activity
Pathways			Phase I - Functionalization of compounds
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 26663301)	Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		16 interacting genes: ABLIM2 ASGR1 C3orf52 CTSA CYB5B CYBC1 FAM3C GABARAPL1 GABARAPL2 IGFBP5 PRAP1 SUMO2 TSPO2 UBIAD1 VAMP3 ZFPL1	48 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A6 SLC16A2 SLC39A9 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B
Entrez ID		113146	80777
HPRD ID		12261	13106
Ensembl ID		ENSG00000185567	ENSG00000103018
Uniprot IDs		Q8IVF2	O43169
PDB IDs		4CN0	3NER
Enriched GO Terms of Interacting Partners?
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