CYB5B and SDHAF4

Data Source:
BioGRID (two hybrid)

		CYB5B	SDHAF4
Description		cytochrome b5 type B	succinate dehydrogenase complex assembly factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Cellular_component Mitochondrion Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Mitochondrial Matrix
	Molecular Function	Protein Binding Enzyme Activator Activity Electron Transfer Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Molecular_function Protein Binding Succinate Dehydrogenase (ubiquinone) Activity
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Electron Transport Chain Regulation Of Catalytic Activity	Mitochondrial Respiratory Chain Complex II Assembly Innate Immune Response Cellular Respiration
Pathways		Phase I - Functionalization of compounds
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		48 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A6 SLC16A2 SLC39A9 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	3 interacting genes: CD81 CYB5B UPK1B
Entrez ID		80777	135154
HPRD ID		13106	12888
Ensembl ID		ENSG00000103018	ENSG00000154079
Uniprot IDs		O43169	Q5VUM1
PDB IDs		3NER
Enriched GO Terms of Interacting Partners?
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