CHRM1 and GPRASP2

Data Source:
HPRD (in vitro)

		CHRM1	GPRASP2
Description		cholinergic receptor muscarinic 1	G protein-coupled receptor associated sorting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Dendrite Axon Terminus Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Cholinergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Nucleus Cytoplasm
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Nervous System Development Regulation Of Locomotion Positive Regulation Of Ion Transport Saliva Secretion Cognition Regulation Of Postsynaptic Membrane Potential Regulation Of Glial Cell Proliferation Positive Regulation Of Intracellular Protein Transport G Protein-coupled Serotonin Receptor Signaling Pathway	Hematopoietic Stem Cell Homeostasis
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs		Cevimeline Tramadol Succinylcholine Trospium Oxyphenonium Benzatropine Ziprasidone Disopyramide Amitriptyline Ipratropium Olanzapine Metixene Terfenadine Buclizine Clozapine Doxylamine Trihexyphenidyl Oxyphencyclimine Procyclidine Profenamine Loxapine Carbamoylcholine Promazine Hyoscyamine Cyproheptadine Meperidine Imipramine Methscopolamine bromide Chlorpromazine Gallamine triethiodide Darifenacin Tridihexethyl Triflupromazine Anisotropine methylbromide Nortriptyline Amoxapine Amoxapine Cinnarizine Atropine Nicardipine Pirenzepine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Clidinium Propiomazine Propantheline Dicyclomine Minaprine Tropicamide Biperiden Brompheniramine Flupentixol Cocaine Maprotiline Methantheline Cycrimine Cyclopentolate Glycopyrronium Bethanechol Tolterodine Oxybutynin Promethazine Pilocarpine Doxepin Flavoxate Desipramine Escitalopram Ketamine Quetiapine Diphenidol Metoclopramide Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin Molindone Staurosporine Acetylcholine Arecoline Mepenzolate NGX267 ALKS 27 ACP-104 Pizotifen Fesoterodine Hexocyclium Aclidinium Umeclidinium Trimebutine Dosulepin Etoperidone Imidafenacin Pyrantel Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS		Urate levels ( 31578528)
Interacting Genes		5 interacting genes: CDC14A GNAI2 GPRASP1 GPRASP2 RGS7	52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 RTL10 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688
Entrez ID		1128	114928
HPRD ID		00338	06612
Ensembl ID		ENSG00000168539	ENSG00000158301
Uniprot IDs		P11229 Q53XZ3	B3KW05 Q96D09
PDB IDs		5CXV 6OIJ 6WJC
Enriched GO Terms of Interacting Partners?
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