GPRASP2 and HTR7

Data Source:
HPRD (in vitro)

		GPRASP2	HTR7
Description		G protein-coupled receptor associated sorting protein 2	5-hydroxytryptamine receptor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Hematopoietic Stem Cell Homeostasis	Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Circadian Rhythm Blood Circulation Vasoconstriction G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Methysergide Cabergoline Zolmitriptan Amitriptyline Clozapine Loxapine Cyproheptadine Imipramine Chlorpromazine Haloperidol Amoxapine Lisuride Paroxetine Risperidone Epinastine Cyclobenzaprine Maprotiline Dopamine Ergoloid mesylate Bromocriptine Quetiapine Aripiprazole Chlorprothixene Paliperidone Iloperidone Lofexidine Mianserin Asenapine Amisulpride Lurasidone Vortioxetine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine SB-269970 Aripiprazole lauroxil
Diseases
GWAS			Alzheimer disease and age of onset ( 26830138) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Midgestational total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) White matter microstructure (global fractional anisotropy) ( 24736177)
Interacting Genes		52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 RTL10 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688	2 interacting genes: GPRASP1 GPRASP2
Entrez ID		114928	3363
HPRD ID		06612	01639
Ensembl ID		ENSG00000158301	ENSG00000148680
Uniprot IDs		B3KW05 Q96D09	P34969
PDB IDs
Enriched GO Terms of Interacting Partners?
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