RAB1B and MICAL3

Data Source:
HPRD (two hybrid, in vitro)

		RAB1B	MICAL3
Description		RAB1B, member RAS oncogene family	microtubule associated monooxygenase, calponin and LIM domain containing 3
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Spindle Cytosol Plasma Membrane Cell Cortex Cell Projection Intercellular Bridge Flemming Body
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Actin Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Metal Ion Binding FAD Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Virion Assembly Post-translational Protein Modification COPII Vesicle Coating Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly	Exocytosis Cytoskeleton Organization Cell Cycle Actin Filament Depolymerization Cell Division
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Body mass index ( 28552196) Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) FEV1 ( 30804560) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Pancreatic cancer ( 29422604) Peak expiratory flow ( 30804560) Presence of antiphospholipid antibodies ( 23509613) Response to hepatitis B vaccine ( 29534301) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RABIF RUSC2 SMARCC2 TOMM40L	1 interacting genes: RAB1B
Entrez ID		81876	57553
HPRD ID		11469	19352
Ensembl ID		ENSG00000174903	ENSG00000243156
Uniprot IDs		Q9H0U4	Q7RTP6
PDB IDs		3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK 6SKU	2D88 5SZG 6ICI
Enriched GO Terms of Interacting Partners?
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