RAB1B and GDI1

Data Source:
HPRD (in vivo)

		RAB1B	GDI1
Description		RAB1B, member RAS oncogene family	GDP dissociation inhibitor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath
	Molecular Function	GTPase Activity Protein Binding GTP Binding	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Virion Assembly Post-translational Protein Modification COPII Vesicle Coating Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Non-syndromic X-linked mental retardation
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		11 interacting genes: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RABIF RUSC2 SMARCC2 TOMM40L	15 interacting genes: CDC42 EPB41 GNL1 LNX1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4
Entrez ID		81876	2664
HPRD ID		11469	02114
Ensembl ID		ENSG00000174903	ENSG00000203879
Uniprot IDs		Q9H0U4	A0A0S2Z3X8 P31150
PDB IDs		3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK 6SKU
Enriched GO Terms of Interacting Partners?
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