AQP3 and SSMEM1

Data Source:
BioGRID (two hybrid)

		AQP3	SSMEM1
Description		aquaporin 3 (Gill blood group)	serine rich single-pass membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Identical Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Immune System Process Renal Water Homeostasis Water Transport Glycerol Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport Cellular Response To Oxygen-glucose Deprivation
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs		Sennosides
Diseases
GWAS		Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)	Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN	95 interacting genes: ALG3 APOA2 AQP1 AQP10 AQP3 ATP6V0C BET1 BLCAP C11orf24 C1QL4 C4orf3 C5 CCL4L2 CDS2 CLRN2 CMTM7 CSGALNACT2 CTSA CXCL16 CXCL9 CYB561 CYBC1 DEFB103A DEFB103B DEFB121 EFNA5 EMD ERG28 ERMP1 FAM3C FATE1 FDPS FPR2 GJB2 GPHB5 GPR151 HMOX2 LAT LEPROTL1 LNPEP MARCHF2 MCRS1 MFSD12 MFSD5 MFSD6 MIP MMD2 MS4A13 NIPAL4 NRM PGAP2 PLPP1 PLPP4 PLPP6 PLPPR2 RHD RTP2 RUSF1 S1PR5 SERP1 SLC35A1 SLC35C2 SLC35E3 SLC38A1 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 STX8 TAP1 TAS2R10 TLCD1 TM6SF2 TMEM128 TMEM14A TMEM14C TMEM203 TMEM218 TMEM222 TMEM239 TMEM243 TMEM45A TMEM60 TMEM86A TMEM86B TMEM97 TMPPE TNF TRARG1 UNC93B1 UPK1B VAMP4 YIPF6 ZFPL1
Entrez ID		360	136263
HPRD ID		08970	14060
Ensembl ID		ENSG00000165272	ENSG00000165120
Uniprot IDs		A0A2R8Y2R4 Q92482	A0A3B3ISA2 A4D1L0 Q8WWF3
PDB IDs
Enriched GO Terms of Interacting Partners?
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