CORO1A and FSD2

Data Source:
BioGRID (two hybrid, two hybrid)

		CORO1A	FSD2
Description		coronin 1A	fibronectin type III and SPRY domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Cytosol Actin Filament Plasma Membrane Cell-cell Junction Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Protein-containing Complex Phagocytic Vesicle Extracellular Exosome Glutamatergic Synapse	Nucleus Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Actin Binding Actin Monomer Binding Protein Binding Protein C-terminus Binding Cytoskeletal Protein Binding Myosin Heavy Chain Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Actin Filament Binding	Protein Binding
	Biological Process	Immunological Synapse Formation Phagolysosome Assembly Calcium Ion Transport Phagocytosis Actin Filament Organization Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Leukocyte Chemotaxis Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Regulation Of Actin Cytoskeleton Organization Nerve Growth Factor Signaling Pathway Positive Regulation Of T Cell Proliferation T Cell Homeostasis Natural Killer Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Chemotaxis Negative Regulation Of Actin Nucleation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4
Pathways		Prevention of phagosomal-lysosomal fusion
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hodgkin's lymphoma ( 30194254) Tonsillectomy ( 27182965 28928442)	HDL cholesterol levels ( 32203549) Tourette syndrome ( 30818990)
Interacting Genes		19 interacting genes: ACTB FHL3 FSD2 GIT2 GOLGA2 IFT20 LMO2 MAGEA11 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1	94 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 ESD EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26
Entrez ID		11151	123722
HPRD ID		05414	17291
Ensembl ID		ENSG00000102879	ENSG00000186628
Uniprot IDs		A0A024R611 P31146	A1L4K1 B7ZM05
PDB IDs
Enriched GO Terms of Interacting Partners?
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