CORO1A and GIT2

Data Source:
BioGRID (two hybrid)

		CORO1A	GIT2
Description		coronin 1A	GIT ArfGAP 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Cytosol Actin Filament Plasma Membrane Cell-cell Junction Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Protein-containing Complex Phagocytic Vesicle Extracellular Exosome Glutamatergic Synapse	Nucleoplasm Focal Adhesion
	Molecular Function	RNA Binding Actin Binding Actin Monomer Binding Protein Binding Protein C-terminus Binding Cytoskeletal Protein Binding Myosin Heavy Chain Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Actin Filament Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Immunological Synapse Formation Phagolysosome Assembly Calcium Ion Transport Phagocytosis Actin Filament Organization Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Leukocyte Chemotaxis Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Regulation Of Actin Cytoskeleton Organization Nerve Growth Factor Signaling Pathway Positive Regulation Of T Cell Proliferation T Cell Homeostasis Natural Killer Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Chemotaxis Negative Regulation Of Actin Nucleation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4	Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Prevention of phagosomal-lysosomal fusion
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hodgkin's lymphoma ( 30194254) Tonsillectomy ( 27182965 28928442)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		19 interacting genes: ACTB FHL3 FSD2 GIT2 GOLGA2 IFT20 LMO2 MAGEA11 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1	48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		11151	9815
HPRD ID		05414	09779
Ensembl ID		ENSG00000102879	ENSG00000139436
Uniprot IDs		A0A024R611 P31146	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs
Enriched GO Terms of Interacting Partners?
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