DMC1 and RAD54B

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		DMC1	RAD54B
Description		DNA meiotic recombinase 1	RAD54 homolog B
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome	Nucleus
	Molecular Function	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding	DNA Binding DNA Helicase Activity RNA Helicase Activity Protein Binding ATP Binding DNA Translocase Activity
	Biological Process	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle	Double-strand Break Repair Via Homologous Recombination Mitotic Recombination Reciprocal Meiotic Recombination Determination Of Adult Lifespan Response To Ionizing Radiation DNA Duplex Unwinding Response To Drug
Pathways		Meiotic recombination
Drugs		Imidazole
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)	Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		19 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 LNX1 MSH4 NIF3L1 PIAS2 PICK1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP SDCBP2 TRIM23 UBE2I	30 interacting genes: ANKRD36BP1 ATPAF2 BAAT CCDC33 CDC23 CSNK1E DMC1 DYRK2 ELOA ENKD1 GMCL1 GORASP2 IGFBP3 LNX1 MDM4 MYO15B NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SFRP2 SUMO1 TCEANC TRAPPC6A TRMO UBE2I WRN ZNF580
Entrez ID		11144	25788
HPRD ID		04099	05049
Ensembl ID		ENSG00000100206	ENSG00000197275
Uniprot IDs		Q14565	O95073 Q9Y620
PDB IDs		1V5W 2ZJB 4HYY 6R3P
Enriched GO Terms of Interacting Partners?
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