DMC1 and C1orf112

Data Source:
BioGRID (two hybrid, two hybrid)

		DMC1	C1orf112
Description		DNA meiotic recombinase 1	chromosome 1 open reading frame 112
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome
	Molecular Function	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding	Protein Binding
	Biological Process	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle
Pathways		Meiotic recombination
Drugs		Imidazole
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)	Acute anterior uveitis in ankylosing spondylitis ( 32492107) Basophil percentage of white cells ( 32888494) Blood protein levels ( 28240269) Cardiac Troponin-T levels ( 31014085) Eosinophil percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		19 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 LNX1 MSH4 NIF3L1 PIAS2 PICK1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP SDCBP2 TRIM23 UBE2I	5 interacting genes: APP DMC1 FIGNL1 P4HA3 RAD51
Entrez ID		11144	55732
HPRD ID		04099	07694
Ensembl ID		ENSG00000100206	ENSG00000000460
Uniprot IDs		Q14565	A0A024R922 A0A1B0GUP7 A0A1B0GV14 B4E0A9 Q9NSG2
PDB IDs		1V5W 2ZJB 4HYY 6R3P
Enriched GO Terms of Interacting Partners?
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