DMC1 and MSH4

Data Source:
BioGRID (two hybrid, pull down)

		DMC1	MSH4
Description		DNA meiotic recombinase 1	mutS homolog 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome	Synaptonemal Complex Nucleus Chromosome Recombination Nodule
	Molecular Function	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding	DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Mismatched DNA Binding
	Biological Process	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle	Meiotic Mismatch Repair Resolution Of Meiotic Recombination Intermediates Ovarian Follicle Development Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Spermatogenesis Female Gamete Generation
Pathways		Meiotic recombination	Meiotic recombination
Drugs		Imidazole
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)	Attention function in attention deficit hyperactive disorder ( 26174813) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Serum metabolite levels ( 23093944)
Interacting Genes		19 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 LNX1 MSH4 NIF3L1 PIAS2 PICK1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP SDCBP2 TRIM23 UBE2I	8 interacting genes: DMC1 EIF3F MLH1 MLH3 MSH5 RAD51 RPA1 VBP1
Entrez ID		11144	4438
HPRD ID		04099	03658
Ensembl ID		ENSG00000100206	ENSG00000057468
Uniprot IDs		Q14565	O15457
PDB IDs		1V5W 2ZJB 4HYY 6R3P
Enriched GO Terms of Interacting Partners?
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