KAT7 and CAAP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	CAAP1
Description		lysine acetyltransferase 7	caspase activity and apoptosis inhibitor 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Histone H3-K14 Acetyltransferase Complex Site Of DNA Damage
	Molecular Function	DNA Replication Origin Binding Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding
	Biological Process	Natural Killer Cell Differentiation DNA Replication DNA Repair Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Regulation Of DNA-dependent DNA Replication Initiation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of DNA-templated Transcription, Elongation Histone H3 Acetylation Histone H4 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of DNA Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Nucleotide-excision Repair	Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252) Mean reticulocyte volume ( 32888494)	Adverse response to drug ( 30420678) Attention function in attention deficit hyperactive disorder ( 26174813) Brain volume in infants (grey matter) ( 28763065) Loneliness ( 27629369)
Interacting Genes		44 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 MCRS1 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	4 interacting genes: APP KAT7 PTN XRCC4
Entrez ID		11143	79886
HPRD ID		07135	12981
Ensembl ID		ENSG00000136504	ENSG00000120159
Uniprot IDs		O95251	Q9H8G2
PDB IDs		5GK9 6MAJ 6MAK
Enriched GO Terms of Interacting Partners?
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