KAT7 and PPID

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	PPID
Description		lysine acetyltransferase 7	peptidylprolyl isomerase D
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Histone H3-K14 Acetyltransferase Complex Site Of DNA Damage	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	DNA Replication Origin Binding Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding
	Biological Process	Natural Killer Cell Differentiation DNA Replication DNA Repair Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Regulation Of DNA-dependent DNA Replication Initiation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of DNA-templated Transcription, Elongation Histone H3 Acetylation Histone H4 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of DNA Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Nucleotide-excision Repair	Negative Regulation Of Transcription By RNA Polymerase II Protein Peptidyl-prolyl Isomerization Protein Folding Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Droplet Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Chaperone-mediated Protein Folding Protein-containing Complex Assembly Cellular Response To UV-A
Pathways		HATs acetylate histones	ESR-mediated signaling
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252) Mean reticulocyte volume ( 32888494)	Blood protein levels ( 30072576 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Serum metabolite levels ( 23093944)
Interacting Genes		44 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 MCRS1 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	20 interacting genes: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27
Entrez ID		11143	5481
HPRD ID		07135	11875
Ensembl ID		ENSG00000136504	ENSG00000171497
Uniprot IDs		O95251	E5KN55 Q08752
PDB IDs		5GK9 6MAJ 6MAK
Enriched GO Terms of Interacting Partners?
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