RPP14 and POP4

Data Source:
HPRD (in vitro)

		RPP14	POP4
Description		ribonuclease P/MRP subunit p14	POP4 homolog, ribonuclease P/MRP subunit
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease MRP Activity Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus
Drugs
Diseases
GWAS		Height ( 28552196) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)	Body mass index ( 26426971) Heart rate increase in response to exercise ( 29497042) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277	6 interacting genes: POP1 POP5 RPP14 RPP25 RPP30 RPP38
Entrez ID		11102	10775
HPRD ID		18001	09358
Ensembl ID		ENSG00000163684	ENSG00000105171
Uniprot IDs		O95059	O95707
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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