TMEM115 and SYNE4

Data Source:
BioGRID (two hybrid)

		TMEM115	SYNE4
Description		transmembrane protein 115	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Integral Component Of Membrane Golgi Transport Complex Golgi Cisterna Membrane	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Cell Population Proliferation Protein Transport	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: AQP6 ASPG CREB3 CYB5R3 HTATIP2 MANBAL RABAC1 SYNE4 TLCD4 TMED8 TMX2 ZDHHC17	56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648
Entrez ID		11070	163183
HPRD ID		06144	08776
Ensembl ID		ENSG00000126062	ENSG00000181392
Uniprot IDs		A0A024R2Y2 Q12893	Q8N205
PDB IDs			6R16
Enriched GO Terms of Interacting Partners?
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