SYNE4 and ITM2B

Data Source:
BioGRID (two hybrid)

		SYNE4	ITM2B
Description		spectrin repeat containing nuclear envelope family member 4	integral membrane protein 2B
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Amyloid-beta Binding Protein Binding ATP Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Cellular Protein Metabolic Process
Pathways			Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes		56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648	7 interacting genes: APP BCL2 CREB3 KASH5 LMNA NAALADL2 SYNE4
Entrez ID		163183	9445
HPRD ID		08776	04878
Ensembl ID		ENSG00000181392	ENSG00000136156
Uniprot IDs		Q8N205	A0A384MDP7 Q9Y287
PDB IDs		6R16
Enriched GO Terms of Interacting Partners?
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