TMEM115 and ASPG

Data Source:
BioGRID (two hybrid)

		TMEM115	ASPG
Description		transmembrane protein 115	asparaginase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Integral Component Of Membrane Golgi Transport Complex Golgi Cisterna Membrane	Cytosol
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Asparaginase Activity Lysophospholipase Activity Protein Binding Transferase Activity, Transferring Acyl Groups Other Than Amino-acyl Groups Phosphatidyl Phospholipase B Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Cell Population Proliferation Protein Transport	Cellular Amino Acid Biosynthetic Process Lipid Catabolic Process
Pathways		COPI-mediated anterograde transport	Aspartate and asparagine metabolism
Drugs			Procaine
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Blood metabolite levels ( 24816252) Body mass index ( 26426971) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free asparagine levels ( 30659259) Refractive error ( 32231278) Schizophrenia ( 29483656) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		12 interacting genes: AQP6 ASPG CREB3 CYB5R3 HTATIP2 MANBAL RABAC1 SYNE4 TLCD4 TMED8 TMX2 ZDHHC17	12 interacting genes: C20orf85 CEACAM6 DMRT3 GSDMD MYOZ3 RTP5 SGK1 SHC3 TEKT3 TMEM115 USP2 VPS25
Entrez ID		11070	374569
HPRD ID		06144	19180
Ensembl ID		ENSG00000126062	ENSG00000166183
Uniprot IDs		A0A024R2Y2 Q12893	Q86U10
PDB IDs
Enriched GO Terms of Interacting Partners?
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