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SYNE4 and CLEC7A
Data Source:
BioGRID
(two hybrid)
SYNE4
CLEC7A
Description
spectrin repeat containing nuclear envelope family member 4
C-type lectin domain containing 7A
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Nuclear Outer Membrane
Meiotic Nuclear Membrane Microtubule Tethering Complex
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Protein Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Biological Process
Establishment Of Epithelial Cell Apical/basal Polarity
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Pathways
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Interacting Genes
56 interacting genes:
ABT1
ADIPOQ
BRICD5
C3orf52
CD47
CEP19
CLDN19
CLDN7
CLDN8
CLEC7A
CMTM5
CSGALNACT2
CSNK2B
CXCL9
DEFB121
ECE2
EDDM3B
EMP1
ENTPD3
FAM241B
FATE1
GADD45A
GSK3B
IGFBP5
ITM2B
KLHL12
KLRG1
KTN1
MALL
MARCHF2
NAGK
OCLN
OLFM4
OSTCP1
PAQR5
PLPP6
RIPPLY2
RPS6KA6
SEC22A
SEC23B
SENP2
SFTPC
SLN
SMCO4
TCEA2
TMEM115
TMEM140
TMEM147
TMEM182
TMEM248
TMPRSS4
TRIM69
TSPAN15
VTI1B
ZNF250
ZNF648
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
163183
64581
HPRD ID
08776
08396
Ensembl ID
ENSG00000181392
ENSG00000172243
Uniprot IDs
Q8N205
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
PDB IDs
6R16
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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