SNRNP35 and MAP4K2

Data Source:
BioGRID (two hybrid)

		SNRNP35	MAP4K2
Description		small nuclear ribonucleoprotein U11/U12 subunit 35	mitogen-activated protein kinase kinase kinase kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus	Golgi Membrane Basolateral Plasma Membrane
	Molecular Function	MRNA Binding SnRNA Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing	Activation Of MAPKKK Activity Protein Phosphorylation Vesicle Targeting Immune Response JNK Cascade Activation Of JUN Kinase Activity Intracellular Signal Transduction Innate Immune Response Positive Regulation Of JNK Cascade
Pathways		mRNA Splicing - Minor Pathway
Drugs			Fostamatinib
Diseases
GWAS		Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Serum uric acid levels ( 32514006) Urate levels ( 21768215)
Interacting Genes		16 interacting genes: ANKRD11 APP CCDC57 CKS1B CLK3 ILK MAP4K2 PLEKHF2 SBK3 SNAPC3 SRPK2 SYT17 TAB1 TNFSF11 U2AF1 U2AF1L5	13 interacting genes: DEFB1 HNRNPA2B1 MAP2K4 MAP3K11 MCM3AP-AS1 NACAD POT1 PRDX4 RAB8A SERPINA4 SNRNP35 TRAF2 XRCC6
Entrez ID		11066	5871
HPRD ID		15595	04408
Ensembl ID		ENSG00000184209	ENSG00000168067
Uniprot IDs		A0A024RBU2 Q16560	A0A024R567 Q12851
PDB IDs
Enriched GO Terms of Interacting Partners?
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