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CPSF6 and MIR17
Data Source:
BioGRID
(unspecified method)
CPSF6
MIR17
Description
cleavage and polyadenylation specific factor 6
microRNA 17
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Perichromatin Fibrils
Cytoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Membrane
Nuclear Speck
Interchromatin Granule
Paraspeckles
Ribonucleoprotein Complex
Extracellular Space
Mitochondrion
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Ribosomal Large Subunit Binding
Exon-exon Junction Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Processing
Positive Regulation Of RNA Export From Nucleus
Protein Tetramerization
Protein Heterotetramerization
Pre-mRNA Cleavage Required For Polyadenylation
MRNA Alternative Polyadenylation
Messenger Ribonucleoprotein Complex Assembly
Negative Regulation Of Systemic Arterial Blood Pressure
Outflow Tract Morphogenesis
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Low-density Lipoprotein Particle Clearance
Negative Regulation Of Toll-like Receptor Signaling Pathway
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Blood Pressure
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Phagocytosis
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Positive Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Positive Regulation Of Metalloendopeptidase Activity
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Apoptosome Assembly
Positive Regulation Of Pulmonary Blood Vessel Remodeling
Positive Regulation Of Smooth Muscle Hypertrophy
Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Negative Regulation Of Cellular Senescence
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease
Drugs
Diseases
GWAS
Height (
18391951
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (diuretics) (
31015401
)
Pneumoconiosis in silica exposure (
24986923
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Interacting Genes
48 interacting genes:
APBB1
ARMC7
CSNK2A1
EWSR1
GIN1
ITCH
ITSN2
KLHL12
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR155
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR25
MIR29A
MIR34A
MIR92A1
MIR93
MIRLET7A1
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7F2
NCK2
NEDD4
NUDT21
OTUB2
PLSCR1
PPIL1
PRPF40A
SRSF7
TCERG1
TOLLIP
UBAC1
UBQLN4
USP21
WBP4
WWOX
WWP1
WWP2
YES1
ZMYND19
84 interacting genes:
AIMP1
APOBEC3B
ATXN2L
C1QBP
CELF1
CPSF6
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUM1
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TRMT1L
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZNF346
Entrez ID
11052
406952
HPRD ID
05401
Ensembl ID
ENSG00000111605
ENSG00000284536
Uniprot IDs
Q16630
PDB IDs
3P5T
3P6Y
3Q2S
3Q2T
4B4N
4U0A
4U0B
4WYM
6AY9
6GX9
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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