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MIR15A and TRMT10C
Data Source:
BioGRID
(unspecified method)
MIR15A
TRMT10C
Description
microRNA 15a
tRNA methyltransferase 10C, mitochondrial RNase P subunit
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Nucleus
Nucleoplasm
Mitochondrion
Mitochondrial Matrix
Mitochondrial Ribonuclease P Complex
Mitochondrial Nucleoid
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
TRNA Binding
RNA Binding
Protein Binding
TRNA (guanine-N1-)-methyltransferase Activity
TRNA (adenine-N1-)-methyltransferase Activity
Identical Protein Binding
TRNA (guanine(9)-N(1))-methyltransferase Activity
MRNA (adenine-N1-)-methyltransferase Activity
Biological Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Mitochondrial RNA 5'-end Processing
Positive Regulation Of Mitochondrial Translation
Mitochondrial TRNA Methylation
MRNA Methylation
Mitochondrial TRNA Processing
Mitochondrial TRNA 5'-end Processing
Mitochondrial TRNA 3'-end Processing
Pathways
tRNA processing in the mitochondrion
tRNA modification in the mitochondrion
rRNA processing in the mitochondrion
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30643258
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Diastolic blood pressure (
30224653
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Interacting Genes
73 interacting genes:
AIMP1
AIMP2
C1QBP
CPSF1
DARS1
DDX1
DDX21
DDX3X
DDX49
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PUF60
QARS1
RARS1
RBM14
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM71
TRMT10C
UPF1
UTP20
YBX1
YBX3
ZNF346
3 interacting genes:
MIR15A
MIRLET7A3
MT-TI
Entrez ID
406948
54931
HPRD ID
15240
Ensembl ID
ENSG00000283785
ENSG00000174173
Uniprot IDs
Q7L0Y3
PDB IDs
5NFJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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