CKAP4 and HAMP

Data Source:
BioGRID (two hybrid)

		CKAP4	HAMP
Description		cytoskeleton associated protein 4	hepcidin antimicrobial peptide
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Intercalated Disc Apical Cortex
	Molecular Function	RNA Binding	Hormone Activity Copper Ion Binding
	Biological Process	Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Myeloid Cell Homeostasis Cellular Iron Ion Homeostasis Acute-phase Response Immune Response Receptor Signaling Pathway Via JAK-STAT Aging Response To Iron Ion Response To Zinc Ion Killing Of Cells Of Other Organism Response To Vitamin A Negative Regulation Of Iron Ion Transmembrane Transport Response To Erythropoietin Defense Response To Bacterium Positive Regulation Of Macrophage Activation Response To Ethanol Negative Regulation Of Bone Resorption Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Inflammatory Response Defense Response To Fungus Multicellular Organismal Iron Ion Homeostasis Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Cellular Response To X-ray Liver Regeneration Positive Regulation Of Cellular Protein Catabolic Process Cellular Response To Bile Acid Negative Regulation Of Intestinal Absorption Response To Iron Ion Starvation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases			Hemochromatosis (HFE); Juvenile hemochromatosis (JH)
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)	Irritable bowel syndrome ( 29673008) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 28957414)
Interacting Genes		13 interacting genes: ASCC2 ATF4 DKK1 HAMP LINC01554 MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX WASHC3	4 interacting genes: CKAP4 GLP1R SLC40A1 VKORC1
Entrez ID		10970	57817
HPRD ID		16717	05925
Ensembl ID		ENSG00000136026	ENSG00000105697
Uniprot IDs		A0A024RBH2 Q07065	P81172
PDB IDs			1M4E 1M4F 2KEF 3H0T 4QAE 6WBV
Enriched GO Terms of Interacting Partners?
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