RALBP1 and SYNJ2BP

Data Source:
HPRD (in vitro)

		RALBP1	SYNJ2BP
Description		ralA binding protein 1	synaptojanin 2 binding protein
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GO Annotations	Cellular Component	Cytosol Membrane	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Protein Binding
	Biological Process	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		44 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1
Entrez ID		10928	55333
HPRD ID		09013	15455
Ensembl ID		ENSG00000017797	ENSG00000213463
Uniprot IDs		Q15311	A0A024R670 P57105
PDB IDs		2KWH 2KWI 2MBG	2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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