RALBP1 and CBY1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RALBP1	CBY1
Description		ralA binding protein 1	chibby family member 1, beta catenin antagonist
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GO Annotations	Cellular Component	Cytosol Membrane	Nucleus Nucleoplasm Trans-Golgi Network Centriole Cytosol Nuclear Speck Cell Projection
	Molecular Function	GTPase Activator Activity Protein Binding Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Protein Localization Cell Projection Organization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Protein Homotetramerization Cardiac Muscle Cell Differentiation
Pathways		Rho GTPase cycle	Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		44 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L
Entrez ID		10928	25776
HPRD ID		09013	09676
Ensembl ID		ENSG00000017797	ENSG00000100211
Uniprot IDs		Q15311	A0A024R1L9 A0A087WUW0 Q9Y3M2
PDB IDs		2KWH 2KWI 2MBG	4WRQ
Enriched GO Terms of Interacting Partners?
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