DMRT3 and PRDM14

Data Source:
BioGRID (two hybrid)

		DMRT3	PRDM14
Description		doublesex and mab-3 related transcription factor 3	PR/SET domain 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fertilization Regulation Of Gene Expression Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Response to Homoharringtonine (cytotoxicity) ( 25628645)	Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		86 interacting genes: AKAP8L ASPG ATN1 ATP6V0D1 C11orf1 CCNDBP1 CYSRT1 FHL3 FHL5 FOXN1 FRS3 GPSM1 GRN HSF2BP INCA1 KHDRBS3 KPRP KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LASP1 LMO2 MDFI MEOX2 MGAT5B MID2 MTUS2 MYOZ3 NBPF19 NFKBID NHLRC4 NOTCH2NLA OIP5 PFDN5 PLEKHF2 PLSCR1 PRDM14 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 PSME3 RBPMS REL RFX6 RUSC1 SAT1 SPAG8 TCF4 TLE5 TRAF1 TRIM23 TRIM27 TRIP6 TSC1 TTC19 UBASH3B USP54 WWOX YPEL3 ZFY ZMYND12 ZNF438	67 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CBFA2T2 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GAS8 GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP PALB2 PATZ1 PAX2 PLEKHF2 PPP1R32 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUNX1T1 RUSC1 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835
Entrez ID		58524	63978
HPRD ID		16827	11457
Ensembl ID		ENSG00000064218	ENSG00000147596
Uniprot IDs		Q9NQL9	Q9GZV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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