POSTN and SPART

Data Source:
BioGRID (affinity chromatography technology)

		POSTN	SPART
Description		periostin	spartin
Image
GO Annotations	Cellular Component	Extracellular Space Trans-Golgi Network Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix	Cytoplasm Mitochondrial Outer Membrane Lipid Droplet Cytosol Plasma Membrane Midbody Synapse
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Heparin Binding Metal Ion Binding Cell Adhesion Molecule Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Response To Hypoxia Negative Regulation Of Cell-matrix Adhesion Regulation Of Systemic Arterial Blood Pressure Cell Adhesion Regulation Of Notch Signaling Pathway Response To Mechanical Stimulus Response To Muscle Activity Positive Regulation Of Smooth Muscle Cell Migration Extracellular Matrix Organization Response To Estradiol Wound Healing Cellular Response To Fibroblast Growth Factor Stimulus Cellular Response To Vitamin K Cellular Response To Tumor Necrosis Factor Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Neuron Projection Extension Bone Regeneration Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production	Abscission Negative Regulation Of BMP Signaling Pathway Lipid Droplet Organization Negative Regulation Of Collateral Sprouting In Absence Of Injury Neuromuscular Process Cell Division Regulation Of Mitochondrial Membrane Potential Adipose Tissue Development
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Age-related macular degeneration ( 23326517) Blood protein levels ( 30072576 29875488) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes			22 interacting genes: APP APPL1 DESI2 EPN2 EPS15 GPR35 ITCH MAP3K1 OTUB2 OTUD7B OTULIN PLIN3 PRKAR1A RABGEF1 SMURF1 SMURF2 TUBA1A UBAC1 USP5 WWP2 YOD1 ZFYVE9
Entrez ID		10631	23111
HPRD ID		12295	06170
Ensembl ID		ENSG00000133110	ENSG00000133104
Uniprot IDs		A0A024RDS2 A0A024RDT5 B1ALD9 Q15063	A0A024RDV9 Q8N0X7
PDB IDs		5WT7 5YJG 5YJH	2DL1 4U7I
Enriched GO Terms of Interacting Partners?
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