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AGR2 and POM121
Data Source:
HPRD
(two hybrid)
AGR2
POM121
Description
anterior gradient 2, protein disulphide isomerase family member
POM121 transmembrane nucleoporin
Image
GO Annotations
Cellular Component
Extracellular Space
Endoplasmic Reticulum
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Nuclear Membrane
Host Cell
Molecular Function
Dystroglycan Binding
Epidermal Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
Protein Binding
Nuclear Localization Sequence Binding
Structural Constituent Of Nuclear Pore
Biological Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-substrate Adhesion
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Digestive Tract Morphogenesis
Positive Regulation Of Developmental Growth
Negative Regulation Of Cell Death
Mucus Secretion
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of IRE1-mediated Unfolded Protein Response
Positive Regulation Of PERK-mediated Unfolded Protein Response
Regulation Of Glycolytic Process
RNA Export From Nucleus
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Viral Process
Protein Sumoylation
Viral Transcription
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) (
23648065
)
Iron status biomarkers (ferritin levels) (
28334935
)
Residual cognition (
28441426
)
Type 2 diabetes (dietary heme iron intake interaction) (
23386860
)
Subcutaneous adipose tissue (
22589738
)
Triglyceride levels (
32203549
)
Interacting Genes
87 interacting genes:
ANKRD11
APOBEC3B
APP
ASPH
BORCS8
BORCS8-MEF2B
BRD7
C3
CAMLG
CATSPER1
CCDC90B
CD34
CD68
CDKN2AIPNL
CETN3
CKAP2
CLIC3
CNNM3
CPNE6
CRCP
CREB1
CRMP1
CRYGA
CYB5R2
DAG1
DCAF11
EIF3F
FABP2
FAM110A
FAM117B
GET3
GPSM2
GRB2
GUCA1A
HCK
HMG20A
HSD3B7
IL36RN
IMPDH2
KLHL38
KRT31
LSM1
LYPD3
MBD3
MBLAC1
MED31
MLH1
NDUFB2
NRF1
NRIP1
NSD1
NTAQ1
NUP54
NUP58
NUP62CL
OSTF1
PHC3
POGZ
POLR2L
POM121
PSMA1
PSMB1
PSORS1C2
PTTG2
RBFOX1
RBP5
RIIAD1
RTL4
RUVBL2
SDC3
SGTA
SGTB
SH2D1B
STK16
TCEA2
TFAP2D
THOC1
TLE5
TMEM123
TRAF2
TSTD2
UBE2I
UBQLN1
UBQLN2
UBQLN4
USP20
VEZF1
42 interacting genes:
AGR2
AP1B1
AP2B1
APC
ATXN1
BOLL
BRCA1
CCDC57
CEACAM6
CEP55
CEP76
CERT1
CLDN3
COG6
FAM168B
FXR2
GFAP
GOLGA2
GYG1
HOMER3
JMJD7
KPNA6
LPXN
MAGED1
MORN5
NFKBIA
OTUD6A
PAXIP1
RBPMS
SPAG5
STAT3
TEX11
TFIP11
TOX3
TRAF2
TRAF3
TRIM23
TRIM27
TRIM49
TRIP6
UBQLN2
ZMYND12
Entrez ID
10551
9883
HPRD ID
05896
11448
Ensembl ID
ENSG00000106541
ENSG00000196313
Uniprot IDs
O95994
Q4JM46
Q96HA1
PDB IDs
2LNS
2LNT
5T6W
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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