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SEMA4D and LINC00839
Data Source:
BioGRID
(unspecified method)
SEMA4D
LINC00839
Description
semaphorin 4D
long intergenic non-protein coding RNA 839
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Signaling Receptor Binding
Protein Binding
Semaphorin Receptor Binding
Signaling Receptor Activity
Chemorepellent Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neural Crest Cell Migration
Positive Regulation Of Protein Phosphorylation
Immune Response
Cell Adhesion
Negative Regulation Of Cell Adhesion
Axon Guidance
Regulation Of Cell Shape
Negative Regulation Of Alkaline Phosphatase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Cell Migration
Regulation Of Cell Projection Organization
Negative Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Ossification Involved In Bone Maturation
Negative Regulation Of Osteoblast Differentiation
Positive Regulation Of Collateral Sprouting
Regulation Of Dendrite Morphogenesis
Negative Regulation Of Axon Extension Involved In Axon Guidance
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Negative Chemotaxis
Leukocyte Aggregation
Semaphorin-plexin Signaling Pathway
Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis
Positive Regulation Of Inhibitory Synapse Assembly
Pathways
Sema4D mediated inhibition of cell attachment and migration
Sema4D induced cell migration and growth-cone collapse
Other semaphorin interactions
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Body mass index (
28296344
)
Brain morphology (MOSTest) (
32665545
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Mean spheric corpuscular volume (
32888494
)
Refractive error (
32231278
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
5 interacting genes:
CD72
CRK
LINC00839
PLXNB1
PTPRC
82 interacting genes:
ADAMTS15
AKAP13
ALDH16A1
APOL3
BFSP1
CALM1
CC2D1B
CCDC168
CCDC93
CDC16
CEP192
CEP295NL
CHPF
CIZ1
CLGN
CLPTM1
COPB1
DNAH10
DPEP3
EFL1
EID2
EMX1
FAAP100
FAM13B
FBXL5
HAPLN4
IQCN
IRX4
JAKMIP2
KLK14
KRT1
KRT6B
L1CAM
MEX3A
MEX3B
MEX3C
MEX3D
MICAL2
MYO7A
NDUFA2
NOC4L
NOTCH3
NVL
OS9
P4HB
PABPN1
PALM3
PARP6
PHACTR1
PKD1L2
PLOD3
PNPLA3
POMT2
PRSS1
PRSS3
PTBP1
PTEN
PTPRA
QSOX2
RAPGEF6
RIF1
RPLP2
RPTOR
RYR2
SEMA4D
SEPTIN12
SEPTIN9
SERHL2
SLC7A14
SOWAHB
SREBF2
SYNE1
SYNE3
TAS1R3
TCF24
TMC4
TRO
UBE2S
VANGL1
YAP1
YIPF1
ZFPL1
Entrez ID
10507
84856
HPRD ID
03520
17516
Ensembl ID
ENSG00000187764
ENSG00000185904
Uniprot IDs
Q92854
PDB IDs
1OLZ
3OL2
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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