VTI1B and CREB3

Data Source:
BioGRID (two hybrid)

		VTI1B	CREB3
Description		vesicle transport through interaction with t-SNAREs 1B	cAMP responsive element binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Platelet Alpha Granule Lumen SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Golgi Membrane Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding CAMP Response Element Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Platelet Degranulation Protein Targeting To Vacuole Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane	Regulation Of Transcription By RNA Polymerase II Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Viral Process Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Platelet degranulation	CREB3 factors activate genes CREB3 factors activate genes
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		35 interacting genes: AQP6 ASGR2 CD46 CD79A CLINT1 CRB3 CREB3 ERGIC3 FCGR1A GOLGB1 GPR35 GPX8 JAGN1 KASH5 KLRC1 KRTAP10-7 LDLRAD1 LMNA MANBAL PTPN5 REEP4 RNASEK SLC16A7 SLC35C2 STX1A STX2 STX4 STX7 STX8 SYNE4 TMEM14B TMEM234 TMEM51 TNK2 TRIM59	205 interacting genes: ABHD16A ACKR2 ACSF2 ACSL5 ADTRP AGER AGPAT3 ALG3 ALG8 APH1A APOA2 APOD APPBP2 AQP1 AQP2 AQP4 AQP5 ATF3 ATF4 ATP6AP2 ATP6V0C BCAP29 BCAT2 BCL2L1 BIK BNIP2 BNIP3 BTN2A2 C2 C3orf52 CACFD1 CCR1 CD207 CD82 CDS2 CEBPG CELA3A CES1 CFHR5 CGRRF1 CHMP7 CLCN7 CLDN19 CLDND2 CLP1 CMTM5 CNPY3 CREB3L1 CREB3L3 CT45A5 CTSW CYB561 CYB5B CYBC1 CYBRD1 CYP4F2 DDIT3 DNAJC30 DOLK DRAM1 EBP EMC6 EMD ERG28 FA2H FAM3A FAM3C FDFT1 FDPS FIS1 FMO1 FMO3 FXYD3 FXYD6 GJA1 GJB2 GYPA HCFC1 HDAC3 HMOX1 HVCN1 ICAM4 IGFBP5 ITM2B JUN KCNK1 KLHL30-AS1 KRTCAP2 LAT LHFPL5 LILRB5 LMBR1L LMNA LPCAT2 LTA MAL2 MALL MARCHF5 MFSD11 MFSD5 MGST2 MRPL57 MS4A1 MYADM NAA10 NDUFB6 NEU1 NFE2L2 NFE2L3 NFIL3 NKG7 NRG4 ORMDL1 OS9 P4HA2 PLLP PLN PLP1 PLPP1 PLTP PMP22 PNLIPRP1 PSENEN PTCH1 PTDSS1 PTPN9 RAB23 RABAC1 RHEB RIMS3 RPRM RPS3A RRAS2 RUSF1 SACM1L SAR1B SCAMP4 SCAMP5 SCLY SCP2 SEC22B SEC61G SELENOK SERINC1 SFT2D2 SFTPC SFXN3 SHMT2 SLC19A3 SLC29A1 SLC29A2 SLC29A3 SLC2A3 SLC2A4 SLC30A2 SLC35C2 SLC38A1 SLC39A13 SLC41A2 SLC41A3 SLC49A3 SLC50A1 SLC7A9 SPOCK3 SQLE ST6GAL2 STARD3 STX7 STX8 SYNGR1 SYNPR TAP1 TECR TIMM17B TIMM23B TM4SF4 TMEM100 TMEM115 TMEM140 TMEM14A TMEM14B TMEM14C TMEM19 TMEM203 TMEM222 TMEM230 TMEM234 TMEM243 TMEM51 TMEM54 TRAM1 TRAM1L1 TSPAN2 TSPAN4 TSPAN7 TTLL5 UBE2J1 UNC50 USE1 VKORC1 VTI1B YIPF2 ZDHHC11 ZDHHC21 ZDHHC9
Entrez ID		10490	10488
HPRD ID		04440	07339
Ensembl ID		ENSG00000100568	ENSG00000107175
Uniprot IDs		Q9UEU0	O43889
PDB IDs		2V8S
Enriched GO Terms of Interacting Partners?
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