LRRK1 and KIF20A

Data Source:
BioGRID (pull down)

		LRRK1	KIF20A
Description		leucine rich repeat kinase 1	kinesin family member 20A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Golgi Apparatus Spindle Kinesin Complex Microtubule Midbody Cleavage Furrow Intercellular Bridge
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Kinase Binding
	Biological Process	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction	Mitotic Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Protein Transport Regulation Of Cytokinesis Midbody Abscission
Pathways			MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		51 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP VGLL4	6 interacting genes: CDC14A FAM214B LRRK1 RAB6A RAB6B ZRANB2
Entrez ID		79705	10112
HPRD ID		14319	09292
Ensembl ID		ENSG00000154237	ENSG00000112984
Uniprot IDs		Q38SD2	O95235
PDB IDs			6YIP
Enriched GO Terms of Interacting Partners?
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