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RAPGEF3 and PNMA1
Data Source:
BioGRID
(two hybrid)
RAPGEF3
PNMA1
Description
Rap guanine nucleotide exchange factor 3
PNMA family member 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Microvillus
Endomembrane System
Membrane
Lamellipodium
Filopodium
Cortical Actin Cytoskeleton
Extracellular Exosome
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Domain Specific Binding
CAMP Binding
Protein Binding
Biological Process
Angiogenesis
Signal Transduction
CAMP-mediated Signaling
Rap Protein Signal Transduction
Positive Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion
Positive Regulation Of GTPase Activity
Positive Regulation Of Angiogenesis
Positive Regulation Of Protein Export From Nucleus
Regulation Of Insulin Secretion
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion
Establishment Of Endothelial Barrier
Cellular Response To CAMP
Positive Regulation Of Protein Acetylation
Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Histone H3-K9 Acetylation
Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Apoptotic Process
Pathways
Integrin signaling
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Regulation of insulin secretion
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Body mass index (
29273807
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Platelet distribution width (
32888494
)
Waist-to-hip ratio adjusted for BMI (additive genetic model) (
30778226
)
Interacting Genes
14 interacting genes:
AP1M1
AP2B1
DAPK1
DDX6
EXOC8
MAP1A
OARD1
PNMA1
RAP1A
RAP2A
RRAS2
TGFB1
UFSP1
ZRANB1
167 interacting genes:
ABHD17A
AGTR1
ANKRD36BP1
APTX
ARHGEF6
ARID5A
ASMTL
ATP5PO
ATP6V1G1
ATXN7
BEX2
BYSL
C1orf109
C21orf58
C8orf33
CARHSP1
CBX8
CCDC146
CCDC187
CCDC198
CCDC33
CCNG1
CCP110
CDK18
CFAP53
CHIC2
CHMP2B
CNNM3
COX5B
CTNNA3
DAXX
DCTN4
EAF2
EHHADH
ENKD1
FAM107A
FAM110A
FAM161A
FAM161B
FBF1
FBXL18
FEM1C
FMNL2
FOXD4L1
FOXD4L3
GADD45GIP1
GATA1
GEM
GPANK1
GPR25
GRAP2
GTPBP10
HAPLN2
HCK
HDAC4
HGS
HNRNPLL
HOXB9
IGFN1
INO80B
IVD
KANSL1
KAT2B
LAGE3
LENG1
LIN37
LMO3
LNX1
LSM2
MAB21L2
MACIR
MARK4
MCM7
MED8
METTL17
MRPL10
MRPL11
MRPL23
MSI1
MYO15B
MYOZ1
NIF3L1
NPBWR2
NSMF
NTAQ1
NUDT16L1
PARD3
PARD6B
PCGF6
PER1
PIN1
PIN4
PKN1
PKN3
PNMA5
PNMA6A
POLDIP3
POLL
POLM
PRKAB2
PRKCG
PRKCI
PRPF18
PRPF31
PSMA1
RAD51D
RAPGEF3
RBM41
RPP25
RPP25L
RSPH9
RSRC2
RTP5
RUSC1
SCAND1
SCNM1
SDCBP
SEMA4C
SH2D4A
SHC3
SHISA3
SLC25A48
SLIRP
SMIM3
SNRPB
SNRPB2
SPATC1L
SPG7
SSX2IP
STAMBPL1
SUV39H2
TASOR2
TCEA2
TCEANC
TCL1B
TEAD4
TMSB4X
TNNI1
TNNT1
TRIM42
TRIM73
TRPV6
TSHZ2
TSPYL4
TTC23
TTC9C
TXNDC9
UBQLN1
UBQLN4
URB1-AS1
USP2
VAV2
VBP1
VPS9D1
WDR25
WT1-AS
ZC2HC1C
ZCCHC12
ZFYVE26
ZG16B
ZNF148
ZNF35
ZNF410
ZNF438
ZNF564
ZNF581
ZNF688
Entrez ID
10411
9240
HPRD ID
06928
04926
Ensembl ID
ENSG00000079337
ENSG00000176903
Uniprot IDs
O95398
Q99777
Q8ND90
PDB IDs
6H7E
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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