ZNF267 and ATP6V0A1

Data Source:
BioGRID (two hybrid)

		ZNF267	ATP6V0A1
Description		zinc finger protein 267	ATPase H+ transporting V0 subunit a1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Metal Ion Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Toxin Transport Proton Transmembrane Transport
Pathways		Generic Transcription Pathway	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS			Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: ADORA2B ATP6V0A1 EPHA7 TRIM54	7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267
Entrez ID		10308	535
HPRD ID		06883	01886
Ensembl ID		ENSG00000185947	ENSG00000033627
Uniprot IDs		Q14586	Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs
Enriched GO Terms of Interacting Partners?
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