SAP18 and RNPS1

Data Source:
BioGRID (biochemical, pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology)

		SAP18	RNPS1
Description		Sin3A associated protein 18	RNA binding protein with serine rich domain 1
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Splicing, Via Spliceosome	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: DEF6 ERBB3 HDAC1 IKZF1 INCA1 NOL12 NTAQ1 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2	62 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKAPD1 NKTR PICK1 PIN1 PNN PRPF38A PSTPIP1 RBM8A RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF11 SRSF3 SRSF4 SRSF6 SRSF7 SRSF9 STX11 TAF2 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZRANB1 ZSCAN30
Entrez ID		10284	10921
HPRD ID		04256	07341
Ensembl ID		ENSG00000150459	ENSG00000205937
Uniprot IDs		O00422	D3DU92 H3BMS0 Q15287
PDB IDs		2HDE	4A8X
Enriched GO Terms of Interacting Partners?
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