RNPS1 and U2AF1

Data Source:
BioGRID (two hybrid, two hybrid)

		RNPS1	U2AF1
Description		RNA binding protein with serine rich domain 1	U2 small nuclear RNA auxiliary factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Blood and toenail selenium levels ( 25343990)
Interacting Genes		62 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKAPD1 NKTR PICK1 PIN1 PNN PRPF38A PSTPIP1 RBM8A RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF11 SRSF3 SRSF4 SRSF6 SRSF7 SRSF9 STX11 TAF2 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZRANB1 ZSCAN30	51 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		10921	7307
HPRD ID		07341	01871
Ensembl ID		ENSG00000205937	ENSG00000160201
Uniprot IDs		D3DU92 H3BMS0 Q15287	P0DN76 Q01081 Q7Z780
PDB IDs		4A8X	1JMT
Enriched GO Terms of Interacting Partners?
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