RNPS1 and SRP54

Data Source:
HPRD (two hybrid, in vivo)

		RNPS1	SRP54
Description		RNA binding protein with serine rich domain 1	signal recognition particle 54
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding	RNA Binding GTPase Activity Protein Binding GTP Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome	SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Neutrophil Chemotaxis Granulocyte Differentiation Exocrine Pancreas Development Protein Targeting To ER
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		62 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKAPD1 NKTR PICK1 PIN1 PNN PRPF38A PSTPIP1 RBM8A RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF11 SRSF3 SRSF4 SRSF6 SRSF7 SRSF9 STX11 TAF2 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZRANB1 ZSCAN30	2 interacting genes: RNPS1 SRP19
Entrez ID		10921	6729
HPRD ID		07341	05330
Ensembl ID		ENSG00000205937	ENSG00000100883
Uniprot IDs		D3DU92 H3BMS0 Q15287	P61011
PDB IDs		4A8X	1MFQ 1QB2 5L3Q 6Y2Z 6Y30 6Y31 6Y32
Enriched GO Terms of Interacting Partners?
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