U2AF1L5 and SRSF3

Data Source:
BioGRID (two hybrid)

		U2AF1L5	SRSF3
Description		U2 small nuclear RNA auxiliary factor 1 like 5	serine and arginine rich splicing factor 3
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck U2AF Complex	Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
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Diseases
GWAS			Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		15 interacting genes: AP1B1 AP2B1 CARNMT1 EFHC2 HNRNPK KRT1 KRT75 MEOX2 MLH1 SNRNP35 SRRM4 SRSF3 TRA2B U2AF2 ZNF417	39 interacting genes: APP CHD1 CIRBP CLK1 CLK2 CLK3 CNNM3 DUX4 EXOSC6 GEMIN2 HNRNPK IL7R LNX1 NXF1 PCBP1 PCBP2 PCBP3 PCDHB14 PRPF31 RBM3 RBM7 RBMX RBMY1A1 RNPS1 RPL9 SCAF11 SDCBP SREK1 SRPK1 SRPK2 SRSF2 SRSF8 TRA2B U2AF1 U2AF1L5 U2AF2 YWHAB YWHAG YWHAQ
Entrez ID		102724594	6428
HPRD ID			04530
Ensembl ID		ENSG00000275895	ENSG00000112081
Uniprot IDs		P0DN76 Q01081	B2R6F3 P84103
PDB IDs		1JMT	2I2Y 2I38
Enriched GO Terms of Interacting Partners?
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