MAL and KCNA1

Data Source:
BioGRID (two hybrid)

		MAL	KCNA1
Description		mal, T cell differentiation protein	potassium voltage-gated channel subfamily A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft	Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Dendrite Cytoplasmic Vesicle Paranode Region Of Axon Presynaptic Membrane Neuronal Cell Body Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Transmembrane Transporter Activity Disordered Domain Specific Binding Voltage-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Voltage-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization	Startle Response Potassium Ion Transport Regulation Of Muscle Contraction Chemical Synaptic Transmission Neuroblast Proliferation Cell Communication By Electrical Coupling Magnesium Ion Homeostasis Neuronal Action Potential Hippocampus Development Neuronal Signal Transduction Cellular Protein Localization Regulation Of Membrane Potential Neuromuscular Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Protein Homooligomerization Regulation Of Postsynaptic Membrane Potential Cellular Response To Magnesium Ion Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Positive Regulation Of Voltage-gated Potassium Channel Activity
Pathways			Voltage gated Potassium channels
Drugs			Enflurane Amitriptyline Isoflurane Methoxyflurane Promethazine Miconazole Desflurane Dalfampridine Tetraethylammonium Amifampridine
Diseases			Episodic ataxias
GWAS
Interacting Genes		81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35C2 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7	16 interacting genes: APOL2 DLG1 DLG4 DOLK FCER1G GPR152 GPR42 IER3IP1 JAGN1 KCNA10 KCNA3 KCNE4 MAL SGTA TMEM14B TMEM86A
Entrez ID		4118	3736
HPRD ID		01789	08885
Ensembl ID		ENSG00000172005	ENSG00000111262
Uniprot IDs		A0A024RE19 P21145	Q09470
PDB IDs			2AFL
Enriched GO Terms of Interacting Partners?
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