MAL and IL20RB

Data Source:
BioGRID (two hybrid)

		MAL	IL20RB
Description		mal, T cell differentiation protein	interleukin 20 receptor subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath	Cytokine Receptor Activity Protein Binding Interleukin-20 Binding
	Biological Process	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization	Negative Regulation Of Type IV Hypersensitivity Inflammatory Response To Antigenic Stimulus Immune Response-inhibiting Signal Transduction Cytokine-mediated Signaling Pathway Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-4 Production Negative Regulation Of T Cell Proliferation Homeostasis Of Number Of Cells Within A Tissue
Pathways			Interleukin-20 family signaling
Drugs
Diseases
GWAS			Anxiety in major depressive disorder ( 24047446) Autism spectrum disorder or schizophrenia ( 28540026) Height ( 28552196) Initial pursuit acceleration ( 29064472) Menarche (age at onset) ( 25231870) Rheumatoid arthritis ( 30423114 24390342) Sleep duration ( 30531941) White blood cell count ( 32888494)
Interacting Genes		81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35C2 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7	1 interacting genes: MAL
Entrez ID		4118	53833
HPRD ID		01789
Ensembl ID		ENSG00000172005	ENSG00000174564
Uniprot IDs		A0A024RE19 P21145	Q6UXL0
PDB IDs			4DOH 6DF3
Enriched GO Terms of Interacting Partners?
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