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SPRY1 and KRTAP1-1
Data Source:
BioGRID
(two hybrid)
SPRY1
KRTAP1-1
Description
sprouty RTK signaling antagonist 1
keratin associated protein 1-1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Cytosol
Keratin Filament
Molecular Function
Protein Binding
Protein Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Metanephros Development
Ureteric Bud Development
Organ Induction
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Ras Protein Signal Transduction
Animal Organ Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Lens Fiber Cell Differentiation
Biological_process
Keratinization
Pathways
EGFR downregulation
Keratinization
Drugs
Diseases
GWAS
Apolipoprotein B levels (
32203549
)
Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) (
29455858
)
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Irritable bowel syndrome (
24797007
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
Metabolite levels (
23823483
)
Pelvic organ prolapse (
26545240
)
Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) (
29455858
)
Triglyceride levels (
32203549
)
Interacting Genes
83 interacting genes:
ADAM12
ADAMTSL4
ANKRD11
ATXN7
CACNA1A
CCDC57
CDR2L
CHRD
CREB5
CYSRT1
FARS2
FBLN1
FHL5
GEMIN4
GNE
GRB2
GUCD1
HEXIM2
HOXA1
HRG
HSF2BP
INCA1
KPNA2
KPRP
KRT31
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP12-3
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-3
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE2A
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE4A
LCE5A
MB21D2
MDFI
MEOX2
NBPF19
NOTCH2NLA
NTM
OTX1
PCSK5
POLR1C
PRKAA2
PRKAB2
R3HDM2
REL
SMCP
SOCS4
SPRY2
STAT3
TFAP2D
TGM7
UBASH3A
VWC2
YY1
ZNF23
ZNF330
ZNF417
ZNF441
ZNF837
189 interacting genes:
ADAM12
ADAMTSL3
ADAMTSL4
AGXT
AKR7A3
ALDH3B1
ALPP
AQP1
ASPSCR1
ATG9A
BCAM
C10orf62
C11orf87
C19orf38
CAMK2B
CATIP
CATSPER1
CD300LG
CERK
CHIC2
CHRD
CHRNG
CLDN2
CNNM3
CRY2
CSF1
CST2
CTRC
CTSZ
CYHR1
CYSLTR2
CYSRT1
DHRS1
DMRT3
DOCK2
EFNA3
EMC7
FAM221A
FAM71C
FAM76B
FAM90A1
FARS2
FEZF1
FKBP1B
FOXD4L3
FRS3
FZD10
GLP1R
GNE
GRN
GSTP1
GUCD1
HCK
HEY2
HOXA1
HOXB5
HOXB9
HOXC8
HPCAL1
HSBP1
HYAL2
IFITM2
IGSF8
IL16
INS
ITGB4
ITGB5
JOSD1
KLHL38
KLK8
KRT20
KRTAP10-1
KRTAP10-11
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-3
KRTAP13-2
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP4-12
KRTAP4-5
KRTAP5-11
KRTAP5-4
KRTAP5-6
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LNX1
LRFN4
LRRN4
MAGOHB
MAPKBP1
MELTF
MGAT5B
MRGBP
MRPL23
MT1B
MXD3
MXI1
MYOM1
NECTIN2
NECTIN3
NMU
NPDC1
NR1D2
NTM
NUBP2
OLIG3
OR14I1
OTX1
P2RX4
P2RY6
PCSK5
PDE9A
PGAP6
PHLDA1
PRKAB2
PRKAG1
PRPF31
PSMA1
PVR
QPRT
R3HDM2
REM2
RNF111
RPS19BP1
RPS28
RPUSD3
RTN4RL1
SCARF1
SCNM1
SDC3
SEMA3B
SHFL
SLC23A1
SLC43A2
SLC6A20
SLC7A11
SLIT1
SMARCE1
SMCP
SMOC1
SNAI1
SNX18
SPACA9
SPRY1
STK16
TCEANC
TFAP2D
TGFB1
TNP2
TSFM
VASN
VGLL3
VSTM4
WNT11
ZBTB48
ZBTB9
ZDHHC1
ZNF124
ZNF330
ZNF408
ZNF439
ZNF440
ZNF446
ZNF491
ZNF497
ZNF524
ZNF581
ZNF587
ZNF648
ZNF669
ZNF696
ZNF786
ZNF837
Entrez ID
10252
81851
HPRD ID
06782
12304
Ensembl ID
ENSG00000164056
ENSG00000188581
Uniprot IDs
O43609
Q07627
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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