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SPRY1 and LCE1B
Data Source:
BioGRID
(two hybrid)
SPRY1
LCE1B
Description
sprouty RTK signaling antagonist 1
late cornified envelope 1B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Metanephros Development
Ureteric Bud Development
Organ Induction
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Ras Protein Signal Transduction
Animal Organ Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Lens Fiber Cell Differentiation
Keratinization
Pathways
EGFR downregulation
Formation of the cornified envelope
Drugs
Diseases
GWAS
Apolipoprotein B levels (
32203549
)
Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) (
29455858
)
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Irritable bowel syndrome (
24797007
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
Metabolite levels (
23823483
)
Pelvic organ prolapse (
26545240
)
Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) (
29455858
)
Triglyceride levels (
32203549
)
Asthma (
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Interacting Genes
83 interacting genes:
ADAM12
ADAMTSL4
ANKRD11
ATXN7
CACNA1A
CCDC57
CDR2L
CHRD
CREB5
CYSRT1
FARS2
FBLN1
FHL5
GEMIN4
GNE
GRB2
GUCD1
HEXIM2
HOXA1
HRG
HSF2BP
INCA1
KPNA2
KPRP
KRT31
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP12-3
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-3
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE2A
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE4A
LCE5A
MB21D2
MDFI
MEOX2
NBPF19
NOTCH2NLA
NTM
OTX1
PCSK5
POLR1C
PRKAA2
PRKAB2
R3HDM2
REL
SMCP
SOCS4
SPRY2
STAT3
TFAP2D
TGM7
UBASH3A
VWC2
YY1
ZNF23
ZNF330
ZNF417
ZNF441
ZNF837
72 interacting genes:
ADAMTSL4
BEND5
CYSRT1
FBLN1
FUCA2
HOXA1
KRT31
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-3
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP3-1
KRTAP3-2
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1A
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3B
LCE3C
LCE4A
LCE5A
MDFI
MEOX2
NAPSA
NBPF19
NOTCH2NLA
NUFIP2
OTX1
P4HB
RGS17
RGS20
RNF4
SMCP
SPRY1
SPRY2
SPRY3
TGM1
TRIM42
Entrez ID
10252
353132
HPRD ID
06782
17259
Ensembl ID
ENSG00000164056
ENSG00000196734
Uniprot IDs
O43609
Q5T7P3
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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