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HNRNPR and MIR221
Data Source:
BioGRID
(unspecified method)
HNRNPR
MIR221
Description
heterogeneous nuclear ribonucleoprotein R
microRNA 221
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Nucleolus
Endoplasmic Reticulum
Dendrite
Growth Cone
Axon Terminus
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Extracellular Space
Extracellular Vesicle
Molecular Function
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
Circadian Rhythm
RNA Metabolic Process
Negative Regulation Of Catalytic Activity
MRNA Destabilization
Negative Regulation Of Cell Population Proliferation
Response To Glucose
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Interleukin-21 Production
Negative Regulation Of Heterotypic Cell-cell Adhesion
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT
Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Axon Regeneration
Negative Regulation Of Inflammatory Response
Positive Regulation Of Protein Kinase B Signaling
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Necroptotic Process
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Schwann Cell Migration
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Negative Regulation Of Sprouting Angiogenesis
Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Negative Regulation Of Double-strand Break Repair
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Monocyte percentage of white cells (
32888494
)
Interacting Genes
84 interacting genes:
ANKRD28
BMPR2
FARSA
H3-4
IL7R
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PCDHB14
PRMT1
RASD1
RPL26
SMN1
SUMO2
TAB1
87 interacting genes:
ADARB1
AIMP2
APOBEC3B
AQR
C1QBP
CELF1
CPSF1
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
NUDT21
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCB
SART3
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
Entrez ID
10236
407006
HPRD ID
06228
Ensembl ID
ENSG00000125944
ENSG00000207870
Uniprot IDs
B4DMB1
B4DMD1
B4DT28
O43390
Q0VGD6
Q6MZS5
PDB IDs
2DK2
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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