HNRNPR and RPL26

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HNRNPR	RPL26
Description		heterogeneous nuclear ribonucleoprotein R	ribosomal protein L26
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Endoplasmic Reticulum Dendrite Growth Cone Axon Terminus Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Circadian Rhythm RNA Metabolic Process Negative Regulation Of Catalytic Activity MRNA Destabilization	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Viral Transcription Cellular Response To UV Ribosomal Large Subunit Biogenesis Positive Regulation Of Translation Cellular Response To Gamma Radiation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Translation Involved In Cellular Response To UV
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)
Interacting Genes		84 interacting genes: ANKRD28 BMPR2 FARSA H3-4 IL7R MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCDHB14 PRMT1 RASD1 RPL26 SMN1 SUMO2 TAB1	7 interacting genes: APLP2 FBXO7 HNRNPR MDM2 NAA10 NAA15 NAA16
Entrez ID		10236	6154
HPRD ID		06228	04746
Ensembl ID		ENSG00000125944	ENSG00000161970
Uniprot IDs		B4DMB1 B4DMD1 B4DT28 O43390 Q0VGD6 Q6MZS5	P61254
PDB IDs		2DK2	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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