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MIR221 and MSI2
Data Source:
BioGRID
(unspecified method)
MIR221
MSI2
Description
microRNA 221
musashi RNA binding protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Vesicle
Cytoplasm
Cytosol
Polysome
Intracellular Membrane-bounded Organelle
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
Protein Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Response To Glucose
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Interleukin-21 Production
Negative Regulation Of Heterotypic Cell-cell Adhesion
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT
Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Axon Regeneration
Negative Regulation Of Inflammatory Response
Positive Regulation Of Protein Kinase B Signaling
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Necroptotic Process
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Schwann Cell Migration
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Negative Regulation Of Sprouting Angiogenesis
Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Negative Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS
Birth weight (
31043758
)
Chronotype (
30696823
)
Coronary artery calcification (
23870195
)
Decreased low contrast letter acuity in multiple sclerosis (
31289819
)
Emphysema annual change measurement in smokers (adjusted lung density) (
31324189
)
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Freckles (
29895819
)
Height (
31562340
)
Male-pattern baldness (
29146897
27182965
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean platelet volume (
32888494
27863252
)
Metabolite levels (
23823483
)
Neutrophil count (
32888494
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Platelet count (
32888494
)
Plateletcrit (
32888494
27863252
)
Pulse pressure (
30224653
)
Rapid automised naming of pictures (
30741946
)
Refractive error (
32231278
)
Schizophrenia (
28991256
30285260
)
White blood cell count (
32888494
)
Interacting Genes
87 interacting genes:
ADARB1
AIMP2
APOBEC3B
AQR
C1QBP
CELF1
CPSF1
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
NUDT21
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCB
SART3
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
66 interacting genes:
GRB2
HNRNPH1
HNRNPH2
MEOX2
MIR1-1
MIR106A
MIR106B
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29B1
MIR29B2
MIR29C
MIR34A
MIR34B
MIR34C
MIR363
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
Entrez ID
407006
124540
HPRD ID
07438
Ensembl ID
ENSG00000207870
ENSG00000153944
Uniprot IDs
B4DHE8
Q96DH6
PDB IDs
6C8U
6DBP
6NTY
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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