USPL1 and SUMO3

Data Source:
BioGRID (enzymatic study, two hybrid)

		USPL1	SUMO3
Description		ubiquitin specific peptidase like 1	small ubiquitin like modifier 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cajal Body	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body
	Molecular Function	Protein Binding SUMO Binding Ubiquitin Binding SUMO-specific Isopeptidase Activity	Protein Binding Protein Tag Ubiquitin-like Protein Ligase Binding
	Biological Process	Cell Population Proliferation SnRNA Transcription Protein Desumoylation Cajal Body Organization	Protein Sumoylation Negative Regulation Of DNA Binding Regulation Of Protein Localization To Nucleus
Pathways			SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Delirium ( 29631748)
Interacting Genes		5 interacting genes: RANGAP1 SP100 SUMO1 SUMO2 SUMO3	53 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FAM221A FOS HIPK2 HOMEZ HSF1 HSF2 JUN KALRN MAPKAPK3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1 ZBTB33 ZBTB39 ZCCHC12 ZNF496
Entrez ID		10208	6612
HPRD ID		09833	03754
Ensembl ID		ENSG00000132952	ENSG00000184900
Uniprot IDs		A8K1B1 B3KQ64 Q5W0Q7	P55854
PDB IDs			1U4A 2IO1 2MP2 6K5R 6NNQ
Enriched GO Terms of Interacting Partners?
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