SUPT6H and IWS1

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SUPT6H	IWS1
Description		SPT6 homolog, histone chaperone and transcription elongation factor	interacts with SUPT6H, CTD assembly factor 1
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GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin	Nucleus Nucleoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding	Protein Binding
	Biological Process	Blastocyst Formation Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Chromatin Maintenance	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Pulse pressure ( 30578418)	Cardiac troponin-I levels ( 31014085)
Interacting Genes		13 interacting genes: AKT1 CSNK2A1 DNAJB6 EGFR ERBB2 ERCC6 GAB1 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2	10 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1
Entrez ID		6830	55677
HPRD ID		03211	07639
Ensembl ID		ENSG00000109111	ENSG00000163166
Uniprot IDs		Q7KZ85	Q96ST2
PDB IDs		6GME 6GMH 6TED	6EMR
Enriched GO Terms of Interacting Partners?
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