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TMEM239 and S100B
Data Source:
BioGRID
(two hybrid)
TMEM239
S100B
Description
transmembrane protein 239
S100 calcium binding protein B
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Ruffle
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Calcium Ion Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
S100 Protein Binding
Tau Protein Binding
Calcium-dependent Protein Binding
RAGE Receptor Binding
Biological Process
Axonogenesis
Central Nervous System Development
Learning Or Memory
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Pathways
Nuclear signaling by ERBB4
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Advanced glycosylation endproduct receptor signaling
Advanced glycosylation endproduct receptor signaling
TRAF6 mediated NF-kB activation
Drugs
Olopatadine
Calcium
N-Formylmethionine
Arundic acid
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
GWAS
Estimated glomerular filtration rate (
31451708
)
Pulse pressure (
30224653
)
White matter integrity (
23218918
)
Cerebrospinal fluid t-tau:AB1-42 ratio (
28641921
)
Lymphocyte counts (
22286170
)
Interacting Genes
67 interacting genes:
AQP6
ATF7
CD79A
CLDN20
CLRN1
COQ8A
CREB3L1
CREB3L3
CXCL16
DARS2
DCUN1D1
EBP
EMP1
FAM174A
FBXL19
FFAR2
FGD2
FKBP7
FTHL17
FXYD6
GJA8
GPR101
GPR151
GPR42
LENG1
LNX1
MFSD14B
MIEF2
MPP1
MS4A3
MTIF3
MTURN
MYG1
NTAQ1
OCIAD1
ODF4
OTULIN
PDCD1LG2
PNKP
POLI
PSCA
REEP2
RETREG3
S100B
SCAND1
SCN3B
SDCBP
SENP2
SERINC2
SLC10A1
SLC10A6
SLC18A1
SLC34A2
SLC35C2
SNX1
SNX2
SPG21
SSMEM1
SYT16
TBRG4
TIMMDC1
TMEM248
TMEM31
TMX2
TRHR
UBASH3A
USP5
46 interacting genes:
ADTRP
AGER
AGTRAP
AHNAK
ANXA6
BCL2L2
CACYBP
CALM1
CAPZA1
CEP20
CT45A5
DES
DNAJC30
FBXO7
FBXW5
GFAP
GUCY2D
IMP4
IMPA1
IQGAP1
LNX1
MAL2
MAPT
MDM2
MDM4
NDRG1
NKAPD1
PGM1
RABAC1
S100A1
S100A11
S100A2
S100A4
S100A6
S100A9
S100P
S100Z
SDCBP
SPG21
STK38
SUGT1
TMEM159
TMEM239
TNIP1
TP53
VAV1
Entrez ID
100288797
6285
HPRD ID
01505
Ensembl ID
ENSG00000198326
ENSG00000160307
Uniprot IDs
Q8WW34
A0A0S2Z4C5
P04271
PDB IDs
1MQ1
1UWO
2H61
2M49
2PRU
3CZT
3D0Y
3D10
3HCM
4XYN
5CSF
5CSI
5CSJ
5CSN
5D7F
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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