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FRAT1 and KRT18
Data Source:
BioGRID
(two hybrid)
FRAT1
KRT18
Description
FRAT regulator of WNT signaling pathway 1
keratin 18
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Nucleolus
Cytoplasm
Microtubule Organizing Center
Cytosol
Intermediate Filament
Adherens Junction
External Side Of Plasma Membrane
Protein-containing Complex
Centriolar Satellite
Keratin Filament
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Protein Binding
RNA Binding
Structural Molecule Activity
Protein Binding
Scaffold Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
Biological Process
Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Beta-catenin Destruction Complex Disassembly
Cell Cycle
Anatomical Structure Morphogenesis
Response To Fructose
Viral Process
Keratinization
Response To Nutrient Levels
Tumor Necrosis Factor-mediated Signaling Pathway
Golgi To Plasma Membrane CFTR Protein Transport
Negative Regulation Of Apoptotic Process
Intermediate Filament Cytoskeleton Organization
Cornification
Hepatocyte Differentiation
Mesenchymal Stem Cell Differentiation
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Cell-cell Adhesion
Cholangiocyte Apoptotic Process
Pathways
Beta-catenin phosphorylation cascade
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Keratinization
Formation of the cornified envelope
Drugs
Diseases
GWAS
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
White blood cell count (
32888494
)
Cleft lip with or without cleft palate (
28054174
)
Diffusing capacity of carbon monoxide (
30694715
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Interacting Genes
13 interacting genes:
DVL1
GPRASP2
GRN
GSK3B
KCNK5
KRT18
LAMC3
LMAN2
LTBP4
PLSCR1
PSMA3
RABEP2
TDRD7
91 interacting genes:
BBS1
BBS2
BBS4
BBS7
C1orf109
CAMK2A
CASP3
CASP6
CASP7
CASP8
CBL
CCDC146
CCDC85B
CCHCR1
CCNI
CDC5L
CDK1
COL17A1
DEDD
DNAJB6
EFHC1
EGFR
EP300
ESR1
EXOC8
FRAT1
GIT2
GOLGA2
GRN
HAUS1
HGS
HRAS
HSPA1A
HSPA4
HSPA5
HSPB1
IKBKG
KIFC3
KPNA2
KRT15
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT79
KRT8
KRT81
LDOC1
LINC01554
MAPK14
NEFL
NME7
ORC5
PDE4DIP
PIAS4
PKD1
PKP2
PKP3
PNN
POT1
PRKCA
PRKCE
PSTPIP2
RAF1
RCOR3
RHPN2
RPS6KA3
SERPINE1
SHC1
SMARCD1
SVIL
SYCE1
TCHP
TEKT4
TNFRSF1B
TRADD
TSG101
TUBG1
TUBGCP4
TXN2
TXNDC11
UPF2
USH2A
WBP2
YTHDC1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAZ
Entrez ID
10023
3875
HPRD ID
03935
01020
Ensembl ID
ENSG00000165879
ENSG00000111057
Uniprot IDs
Q92837
A0A024RAY2
P05783
PDB IDs
1GNG
3ZRK
3ZRL
3ZRM
4AFJ
5OY4
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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