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LSM1

Description LSM1 homolog, mRNA degradation associated
Image No pdb structure
GO Annotations Cellular Component
  • P-body
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Axon
  • Dendrite
  • Neuronal Cell Body
  • Messenger Ribonucleoprotein Complex
  • Lsm1-7-Pat1 Complex
Molecular Function
  • RNA Cap Binding
  • RNA Binding
  • MRNA Binding
  • Protein Binding
  • Pre-mRNA Binding
Biological Process
  • Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
  • RNA Splicing, Via Transesterification Reactions
  • MRNA Processing
  • RNA Splicing
  • RNA Metabolic Process
  • Stem Cell Population Maintenance
  • Exonucleolytic Catabolism Of Deadenylated MRNA
  • Negative Regulation Of Neuron Differentiation
  • Histone MRNA Catabolic Process
Pathways
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Schizophrenia ( 28991256 22037555 29483656)
Novel Interacting Genes 2 novel interacting genes: GOLGA7 NSD3
Interacting Genes 32 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID 27257
HPRD ID 06281
Ensembl ID ENSG00000175324
Uniprot IDs A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025